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Integrative Structural Biology in the new Instruct-ES Center Madrid – January 29-30, 2026

Integrative Structural Biology in the new Instruct-ES Center

Venue: Auditorio IQF Blas Cabrera 

Date: January 29 – 30, 2026

.Aim:

Structural biology is experiencing an exciting moment in Spain. With the expansion of Instruct-ES, our country is consolidating its position as a key node within the European infrastructure Instruct-ERIC, which drives the study of biological processes at the molecular and atomic levels.

The Instruct-ES Workshop will be a meeting point for researchers, technologists, and facility leaders in cryo-EM, NMR, and X-ray techniques, all sharing a common goal: to build an integrated community that combines methods, talent, and knowledge to tackle the major challenges of modern biology.

Through a series of scientific presentations and open discussions, we will explore how collaboration between centers and shared access to advanced infrastructures can transform the way we study life.

 

INVITED SPEAKERS
CRYOEM
  • Dr. Sergio Cruz- León. Department of Theoretical Biophysics. Max Planck Institute of Biophysics, Frankfurt
  • Prof. Dr. Kay Grünewald. Head of Research Group ‘Structural Cell Biology of Viruses’.
    Professor for Structural Biology; University of Hamburg, Leibniz Institute of Virology, and Centre for Structural Systems Biology (CSSB).
    Scientific Director of CryoEM multiuser facility and Advanced Light and Fluorescence Microscopy core facility at CSSB
NMR
  • Dr. Andrew Baldwin. Professor of Physical and Theoretical Chemistry. Department of Chemistry. University of Oxford
  • Professor Björn Burmann. Department of Chemistry and Molecular Biology.University of Gothenburg
Time-resolved macromolecular crystallography
  • Dr. Tobias Weinert. Senior Scientist, Laboratory of Biomolecular Research. Paul Scherrer Institute, Villigen, Switzerland
Soft X-Ray Tomography
  • Dr. Ana Joaquina Pérez Berná. MISTRAL Beamline, ALBA Synchrotron
Molecular Dynamics
  • Dr. Modesto Orozco. Mechanisms of Disease Unit. IRB, Barcelona
AGENDA
Thursday – January 29
12:00 – 14:00 Reception and lunch
Welcome by Institutional Representatives
14:00 – 14:15

Institutional Welcome:

  • Isabel Diaz, Vice President of Internationalization and Cooperation of the Spanish Research Council CSIC
  • Inmaculada Figueroa, Deputy Director General for International Consortia, Organizations and Research Infrastructures. Ministry of Science, Innovation and Universities
14:15 – 14:30

Instruct-ERIC Welcome:

  • Harald Schwalbe, video recording by Instruct-ERIC Director
  • José-Maria Carazo, Instruct-ERIC Council Chair
Scientific Program
14:30 – 15:00 High-confidence 3D template matching: bridging in situ cryo-ET and multiscale simulations for biological discovery.
Dr. Sergio Cruz- León.
15:00 – 15:30 NMR, EM and biophysics reveal unexpected structure and dynamics within membrane-less organelles
Dr. Andrew Baldwin
15:30 – 16:00 Time-resolved serial crystallography: from slow & simple to fast & fiddly.
Dr. Tobias Weinert
16:00 – 16:30 Coffee break + Network time
16:30 – 17:00 Conformational flexibility and molecular plasticity in herpesvirus entry and egress.
Prof. Dr. Kay Grünewald
17:00 – 17:30 Into the future: towards studying structure and dynamics in the native environment using NMR spectroscopy.
Prof. Björn Burmann
17:30 – 18:00 Hepatitis C, SARS-CoV-2, and West Nile Virus infections and their antiviral treatments monitored by multimodal imaging.
Dr. Ana Joaquina Pérez Berná
18:00 – 18:30

Pushing the frontiers of nucleic acids simulations. The importance of data.
Dr. Modesto Orozco
18:30 – 20:00 Posters – Instruct-Spain Services and Network time
20:00 Cena IPs + Speakers
Instruct ERIC & Imstruct Spain Services Overview
Friday – January 30
09: 00 – 09:30 Instruct ERIC Overview – Claudia Alén Amaro (Head of Operations Instuct ERIC)
09:30 – 09:45 I2PC (Instruct Image Processing Center –  Carlos Oscar Sorzano
09:45 – 10:00 CryoEM (CNB-CSIC) – Javier Chichón
10:00 – 10:15 Red de NMR I (Barcelona)  – Borja Mateo
10:15 – 10:30 Red de NMR II (Madrid) –  Gustavo Titaux
10:30 – 10:45 Red de NMR III (Bilbao) – Óscar Millet
10:45 – 11:15 Coffee Break
11:15 – 11:30 CryoEM (Barcelona) – Pablo Guerra
11:30 – 11:45 BREM (Basque Resource cryoEM) Iban Ubarretxena
11:45– 12:15 ALBA: Judith Juanhuix
12:15 – 13:30

The practical Instruct  details: :

    • Applying for access at the different facililties – Marcos Gragera
    • Applying to pilot projects and Instruct traning offer – Jose Luis Vilas
13:30 – 15:00 Farewell lunch + Network time

 

REGISTRATION

  • Registration Fee: 50€
  • Industrial Registration Fee: 100€
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